The Sioux City Lewis & Clark Interpretive Center and the Betty Strong Encounter Center comprise an almost 20,000-square-foot, private, non-profit cultural complex, built and sustained by Missouri River Historical Development, Inc. (MRHD). The Interpretive Center opened in 2002 to commemorate the Lewis & Clark Bicentennial. It expanded in late 2007 with the opening of the adjoining Betty Strong Encounter Center to fulfill a permanent mission of "commemorating a history of encounters before, during and after the expedition."
Joined by the symbolic Crossroads, these two parts create a Missouri Riverfront home for exhibits, programs, and activities that explore how we live together as diverse people, and how we care for our land, our great river, and other natural resources.
It focuses on present-day Sioux City's part of the trail. Murals and interactive exhibits help explain events of the journey that occurred in and around present-day Sioux City, from late July to early September 1804, including the illness, death, and burial of Sergeant Charles Floyd.
The Expedition as a military operation comes to life in exhibits that use interactive devices, including animatronic mannequins, computers, flip books, stamping stations, text-and-graphic panels, lift-and-drop panels, handpainted murals, a brass-rubbing station, and reproductions of military equipment.